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It is definitely true.

The new generation Anti-deps are largely ineffective. There is only 4 or 5 (aside from tricyclics, prozac being one of 5) that I know of that actually work at a statistically significant level above the placebo rate. Tricyclics are actually very effective, but very old, so they are all generic, hence, no money. Same with prozac... more effective than just about any new anti-dep.

Most I think would actually be worse than a placebo. But the companies get around all this by saying it helps with anxiety, sleep... blah blah blah.

For anyone interested, as I mentioned earlier, I've begun taking Lamotrigine. I'm on the full dose now, and I've found it brilliant. Apart from crazy lucid dreams, which are quite entertaining, no side effects - and I usually get them all.

Anyone with depression that hasn't responded well to other medications, or who has a tendency for random unexplained mood crashes, it's worth a shot - I'd recommend trying it. It is a little expensive though, but for me it is well worth it.

Cheers.

<blockquote data-quote="chops_a_must" data-source="post: 264575" data-attributes="member: 5540">It is definitely true.The new generation Anti-deps are largely ineffective. There is only 4 or 5 (aside from tricyclics, prozac being one of 5) that I know of that actually work at a statistically significant level above the placebo rate. Tricyclics are actually very effective, but very old, so they are all generic, hence, no money. Same with prozac... more effective than just about any new anti-dep.Most I think would actually be worse than a placebo. But the companies get around all this by saying it helps with anxiety, sleep... blah blah blah.For anyone interested, as I mentioned earlier, I&#039;ve begun taking Lamotrigine. I&#039;m on the full dose now, and I&#039;ve found it brilliant. Apart from crazy lucid dreams, which are quite entertaining, no side effects - and I usually get them all.Anyone with depression that hasn&#039;t responded well to other medications, or who has a tendency for random unexplained mood crashes, it&#039;s worth a shot - I&#039;d recommend trying it. It is a little expensive though, but for me it is well worth it.Cheers.</blockquote>

[QUOTE="chops_a_must, post: 264575, member: 5540"] It is definitely true. The new generation Anti-deps are largely ineffective. There is only 4 or 5 (aside from tricyclics, prozac being one of 5) that I know of that actually work at a statistically significant level above the placebo rate. Tricyclics are actually very effective, but very old, so they are all generic, hence, no money. Same with prozac... more effective than just about any new anti-dep. Most I think would actually be worse than a placebo. But the companies get around all this by saying it helps with anxiety, sleep... blah blah blah. For anyone interested, as I mentioned earlier, I've begun taking Lamotrigine. I'm on the full dose now, and I've found it brilliant. Apart from crazy lucid dreams, which are quite entertaining, no side effects - and I usually get them all. Anyone with depression that hasn't responded well to other medications, or who has a tendency for random unexplained mood crashes, it's worth a shot - I'd recommend trying it. It is a little expensive though, but for me it is well worth it. Cheers. [/QUOTE]

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