Coronavirus vaccine news

[SirRumpole]

Could a patent free vaccine end covid ?

There's a new vaccine, and it's cheap to make, free to reproduce and could bring the pandemic to a swift end

Researchers using a decades-old recipe unveil the first COVID vaccine to forego patents and allow drug makers around the world to reproduce it for free, a potential game changer for countries where vaccination rates are behind target.

www.abc.net.au

 

[macca]

Could a patent free vaccine end covid ?

There's a new vaccine, and it's cheap to make, free to reproduce and could bring the pandemic to a swift end

Researchers using a decades-old recipe unveil the first COVID vaccine to forego patents and allow drug makers around the world to reproduce it for free, a potential game changer for countries where vaccination rates are behind target.

www.abc.net.au

The good news it is actually a vaccine rather than a treatment so we might be getting there.

It reads that it is the same type as Novovax so that would raise a question on patent but they both use a proven effective method that has been around for decades so any patent may have expired.

 

[wayneL]

First lot of Pfizer docs got dropped today... Surprised by the lack of comments... Or maybe not

 

[moXJO]

First lot of Pfizer docs got dropped today... Surprised by the lack of comments... Or maybe not

Waiting for the nerds to break it down. It's a boring read.

 

[rederob]

Waiting for the nerds to break it down. It's a boring read.

It's become a non event because most Australians have been double vaxxed, with avery large percentage of these also boosted.
Add that to Omicron not having much effect on the vaxxed, although still impacting those with comorbidities and high age, then the data has now become almost as meaningless as reporting on the flu.

 

[wayneL]

It's become a non event because most Australians have been double vaxxed, with avery large percentage of these also boosted.
Add that to Omicron not having much effect on the vaxxed, although still impacting those with comorbidities and high age, then the data has now become almost as meaningless as reporting on the flu.

Varying opinions on that. Moot point for me and Mrs, so just watching with interest in the fullness of time.

 

[rederob]

Varying opinions on that. Moot point for me and Mrs, so just watching with interest in the fullness of time.

Opinions without data to back them up are as useful as horseshoes without nails.

 

[macca]

sadly, the Omicron variant is giving people better immunity than the vaccines.............. Sadly?

 

[wayneL]

Opinions without data to back them up are as useful as horseshoes without nails.

Never said the opinions were without data, as they were based on the data contained within the Pfizer documents. DYOR on that.

But for your information, with the help of cyanoacrylates, horseshoe nails are not strictly necessary.

Data, bro.

 

[moXJO]

It's become a non event because most Australians have been double vaxxed, with avery large percentage of these also boosted.
Add that to Omicron not having much effect on the vaxxed, although still impacting those with comorbidities and high age, then the data has now become almost as meaningless as reporting on the flu.

This to. I don't really care as I am already vaxed. I didn't vax my 5 year olds and probably won't till I see more benefit.

 

[rederob]

Never said the opinions were without data, as they were based on the data contained within the Pfizer documents.

Your opinions typically lack data, and occasionally are not even opinions but uninformed tweets, a bit like @macca's above at post #1388.

But for your information, with the help of cyanoacrylates, horseshoe nails are not strictly necessary.

Horseshoes were only needed when humans found uses for them other than meat.

 

[rederob]

This to. I don't really care as I am already vaxed. I didn't vax my 5 year olds and probably won't till I see more benefit.

While I am provaxxing, I am not convinced that MRNA type vaccines offer an adequate risk/reward outcome for young people, especially now with Omicron hospitalising comparatively few compared to Delta. In your situation I would do the same.
Omicron also has a habit of breaking through vaccinations whereas it was less likely with earlier variants, so vaccinating the young no longer offers the prospect of reduced chance of infecting others.

 

[wayneL]

Your opinions typically lack data, and occasionally are not even opinions but uninformed tweets, a bit like @macca's above at post #1388.

Horseshoes were only needed when humans found uses for them other than meat.

You freaking idiot, Red. I didn't even offer an opinion all I did was highlight that there was some documents dropped. Now take your ad hominem bull**** and p¹ss off

Jesus!

 

[rederob]

You freaking idiot, Red. I didn't even offer an opinion all I did was highlight that there was some documents dropped. Now take your ad hominem bull**** and p¹ss off

You should read what you write and reflect on it:

Varying opinions on that. Moot point for me and Mrs, so just watching with interest in the fullness of time.

Anyway, I commented on the many posts of yours that have zero data, or are pretty much useless tweets.

 

[moXJO]

I'm hearing of some study that has shown that pfizer converts to DNA in the liver?

This is potentially serious if true and might trigger autoimmune diseases?

Is it disinformation or valid?

 

[sptrawler]

I'm hearing of some study that has shown that pfizer converts to DNA in the liver?

This is potentially serious if true and might trigger autoimmune diseases?

Oh christ don't say that, first the government was canned for using AZ and not getting mRNA quick enough, now if there is an ongoing problem with mRNA, the government will be in the $hit for getting it.
I only hope the media can tell me what to do, it is all so confusing, I guess I will have to watch the project to get some accurate information.

 

[moXJO]

Oh christ don't say that, first the government was canned for using AZ and not getting mRNA quick enough, now if there is an ongoing problem with mRNA, the government will be in the $hit for getting it.
I only hope the media can tell me what to do, it is all so confusing, I guess I will have to watch the project to get some accurate information.

I'm not sure of who, size or validity of the study. But I do think a majority of any effects will be passed off as long covid if there were any.

 

[wayneL]

Hmmm, the plot thickens

 

[moXJO]

Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line

Preclinical studies of COVID-19 mRNA vaccine BNT162b2, developed by Pfizer and BioNTech, showed reversible hepatic effects in animals that received the BNT162b2 injection. Furthermore, a recent study showed that SARS-CoV-2 RNA can be reverse-transcribed and integrated into the genome of human...

www.mdpi.com

Liver trial

 

[moXJO]

Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line

Preclinical studies of COVID-19 mRNA vaccine BNT162b2, developed by Pfizer and BioNTech, showed reversible hepatic effects in animals that received the BNT162b2 injection. Furthermore, a recent study showed that SARS-CoV-2 RNA can be reverse-transcribed and integrated into the genome of human...

www.mdpi.com

Liver trial

This laboratory study from Lund University, Sweden has generated excitement amongst the anti-vaxxers, who claim that the BNT162b2 (Moderna vaccine) can be reverse transcribed to DNA in a liver cell line known as Huh7.

The idea that vaccines can “permanently alter your DNA” is actually not new. It dates back to the time of the first smallpox vaccine in 1796.

Soon after its introduction, cows were caricatured growing from the human anatomy, suggesting that the human body had been altered by the vaccine.

The Pfizer-BioNTech and Moderna vaccines work by instructing our own cells to produce viral proteins, in this instance, spike proteins, which are then recognised by our immune system as foreign.

This in turn triggers the production of long-lasting antibodies, B and T cells that form a defence against any future infection by SARS-CoV-2.

SARS-COV-2 is an RNA virus which does not have the means to produce a DNA transcript, nor can it integrate itself into a host’s genome.

Likewise, it is not biologically possible for the mRNA from the Moderna and Pfizer vaccines to be reverse transcribed into the human DNA.

Secondly, the vaccine mRNA and the human DNA reside in two different compartments of the cell. Our DNA stays in the nucleus, while the vaccine mRNA is only delivered by the nanoparticle into the cytoplasm, thus never entering the nucleus. There are no transporter molecules that can direct the mRNA into the nucleus.

Thirdly, the petri dish experiment used cancer cell lines (Huh7 was derived from a liver cancer) that behaves very differently from normal cell lines and are not representative of normal human cells.

The Huh7 cells used in this laboratory experiment produces an enzyme called the LINE-1 enzyme, which is a reverse transcriptase that converts mRNA into DNA.

Although normal human cells do contain the LINE-1 gene, it is not expressed. In other words, regular human cells do not produce the LINE-1 enzyme to perform the reverse transcription necessary to convert the RNA to DNA.

Furthermore, a laboratory study is not a clinical study, and cannot be extrapolated to make any conclusion about what would happen in a human body.

Fourthly, the Swedish investigators used abnormally high amounts of vaccine in their studies, which is non-physiological. They injected two micrograms for 200,000 cells, which is very excessive, when the physiological dose in the mRNA vaccine is 30 micrograms for the entire human body (30 trillion cells, or 30,000,000,000,000)

Finally, a close analysis of the study shows that the investigators did not provide any evidence of genome integration as claimed. No test was undertaken to confirm integration into the cell DNA.

In fact, in concluding the study, the authors pointed out that their study does not show that the Pfizer vaccine integrates with the liver cell DNA, or alters it in any way.